CDP-choline: (Citicoline) is a highly bioavailable form of choline.
Upon absorption CDP-choline is broken down into choline and cytidine. Cytidine is coverted in the brain to uridine phosphate, which is subsequently converted into cytidine triphosphate at the neuronal level. Its choline portion can be used to make acetylcholine, phosphatidylcholine and sphingomyelin. CDP-choline seems to increase brain glucose metabolism, ATP and phosphocreatine.
CDP-choline appears to increase the synthesis rate and release of dopamine in the striatum, possibly by stimulating tyrosine hydroxylase activity. There’s evidence to suggest CDP-Choline may improve aspects of working memory and executive function for low performing young healthy individuals and aspects of attention for older people and adolescents generally.
For already high performing young people, CDP-choline may actually somewhat impair performance. Systematic reviews have found evidence that CDP-choline helps to mitigate the memory and behavior disturbances associated with age-related cerebral disorders in the short and medium term. CDP-choline seems to have an excellent safety profile and may very well be neuroprotective.
CDP Choline (Citicoline) Supplement, Pharmaceutical Grade, Made in USA (60 Capsules 300mg)
CDP Choline (Citicoline) is a nootropic supplement and is an intermediate in the generation of phosphatidylcholine from choline. Studies have shown supplementation with CDP Choline to improve focus, mental energy, and memory. Supplementation with CDP Choline may also increase dopamine receptor densities.