Rhodiola Rosea: a plant with a long history of medicinal use in Europe and Asia. There’s some evidence to suggest Rhodiola rosea, reduces mental fatigue, physical fatigue and symptoms of depression. Rhodiola rosea reduces stress induced excretion of cortisol and may inhibit AChE and MAO. Rhodiola rosea does not seem to improve cognitive function outside of reducing mental fatigue. Users commonly report acute stimulant-like effects when trying rhodiola rosea for the first time. Those stimulant-like effects may diminish with long-term use.